Planet Four: Terrains - Discovery of Araneiforms Outside of the South Polar Layered Deposits

We present the results of a systematic mapping of seasonally sculpted terrains on the South Polar region of Mars with the Planet Four: Terrains (P4T) online citizen science project. P4T enlists members of the general public to visually identify features in the publicly released Mars Reconnaissance Orbiter CTX images. In particular, P4T volunteers are asked to identify: 1) araneiforms (including features with a central pit and radiating channels known as 'spiders'); 2) erosional depressions, troughs, mesas, ridges, and quasi-circular pits characteristic of the South Polar Residual Cap (SPRC) which we collectively refer to as 'Swiss cheese terrain', and 3) craters. In this work we present the distributions of our high confidence classic spider araneiforms and Swiss cheese terrain identifications. We find no locations within our high confidence spider sample that also have confident Swiss cheese terrain identifications. Previously spiders were reported as being confined to the South Polar Layered Deposits (SPLD). Our work has provided the first identification of spiders at locations outside of the SPLD, confirmed with high resolution HiRISE imaging. We find araneiforms on the Amazonian and Hesperian polar units and the Early Noachian highland units, with 75% of the identified araneiform locations in our high confidence sample residing on the SPLD. With our current coverage, we cannot confirm whether these are the only geologic units conducive to araneiform formation on the Martian South Polar region. Our results are consistent with the current CO2 jet formation scenario with the process exploiting weaknesses in the surface below the seasonal CO2 ice sheet to carve araneiform channels into the regolith over many seasons. These new regions serve as additional probes of the conditions required for channel creation in the CO2 jet process. (Abridged)Comment: accepted to Icarus - Supplemental data files are available at https://www.zooniverse.org/projects/mschwamb/planet-four-terrains/about/results - Icarus print version available at http://www.sciencedirect.com/science/article/pii/S001910351730055

VeSPA: The SuperWASP Variable Star Photometry Archive

SuperWASP Variable Stars is a Zooniverse citizen science project in which the public label photometric light curve plots showing potential variations in stellar brightness. The volunteers label each plot as one of several types of variable star, or as “unknown” or “junk”. Their labels are combined to produce an aggregated classification. We are publishing the first data release from the project via an interactive website called VeSPA. The results can be searched, filtered, and exported in CSV format. Raw FITS data is available to download

A SuperWASP Light Curve Displaying a Single Long-duration Transit: A Jupiter Size Exoplanet in a Very Distant Orbit?

We present the SuperWASP light curve of a 10th magnitude A7V star containing a single, well-defined U-shaped transit-like event lasting around 11 days with a depth of 1.1%. The star is otherwise non-variable throughout the 8 yr duration of the observations. If the event is modeled as an exoplanet transit, it is compatible with a 1.8 RJ exoplanet in a ∼205 au orbit with a period of ∼2200 yr

SuperWASP Variable Stars: Classifying Light Curves Using Citizen Science

We present the first analysis of results from the SuperWASP Variable Stars Zooniverse project, which is aiming to classify 1.6 million phase-folded light curves of candidate stellar variables observed by the SuperWASP all sky survey with periods detected in the SuperWASP periodicity catalogue. The resultant data set currently contains >1 million classifications corresponding to >500,000 object-period combinations, provided by citizen-scientist volunteers. Volunteer-classified light curves have ∼89 per cent accuracy for detached and semi-detached eclipsing binaries, but only ∼9 per cent accuracy for rotationally modulated variables, based on known objects. We demonstrate that this Zooniverse project will be valuable for both population studies of individual variable types and the identification of stellar variables for follow up. We present preliminary findings on various unique and extreme variables in this analysis, including long period contact binaries and binaries near the short-period cutoff, and we identify 301 previously unknown binaries and pulsators. We are now in the process of developing a web portal to enable other researchers to access the outputs of the SuperWASP Variable Stars project

Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension

Vascular Nox (NADPH oxidase)-derived reactive oxygen species and endoplasmic reticulum (ER) stress have been implicated in hypertension. However, relationships between these processes are unclear. We hypothesized that Nox isoforms localize in a subcellular compartment-specific manner, contributing to oxidative and ER stress, which influence the oxidative proteome and vascular function in hypertension. Nox compartmentalization (cell fractionation), O2− (lucigenin), H2O2 (amplex red), reversible protein oxidation (sulfenylation), irreversible protein oxidation (protein tyrosine phosphatase, peroxiredoxin oxidation), and ER stress (PERK [protein kinase RNA-like endoplasmic reticulum kinase], IRE1α [inositol-requiring enzyme 1], and phosphorylation/oxidation) were studied in spontaneously hypertensive rat (SHR) vascular smooth muscle cells (VSMCs). VSMC proliferation was measured by fluorescence-activated cell sorting, and vascular reactivity assessed in stroke-prone SHR arteries by myography. Noxs were downregulated by short interfering RNA and pharmacologically. In SHR, Noxs were localized in specific subcellular regions: Nox1 in plasma membrane and Nox4 in ER. In SHR, oxidative stress was associated with increased protein sulfenylation and hyperoxidation of protein tyrosine phosphatases and peroxiredoxins. Inhibition of Nox1 (NoxA1ds), Nox1/4 (GKT137831), and ER stress (4-phenylbutyric acid/tauroursodeoxycholic acid) normalized SHR vascular reactive oxygen species generation. GKT137831 reduced IRE1α sulfenylation and XBP1 (X-box binding protein 1) splicing in SHR. Increased VSMC proliferation in SHR was normalized by GKT137831, 4-phenylbutyric acid, and STF083010 (IRE1–XBP1 disruptor). Hypercontractility in the stroke-prone SHR was attenuated by 4-phenylbutyric acid. We demonstrate that protein hyperoxidation in hypertension is associated with oxidative and ER stress through upregulation of plasmalemmal-Nox1 and ER-Nox4. The IRE1–XBP1 pathway of the ER stress response is regulated by Nox4/reactive oxygen species and plays a role in the hyperproliferative VSMC phenotype in SHR. Our study highlights the importance of Nox subcellular compartmentalization and interplay between cytoplasmic reactive oxygen species and ER stress response, which contribute to the VSMC oxidative proteome and vascular dysfunction in hypertensio

Planet Four: Probing springtime winds on Mars by mapping the southern polar CO2 jet deposits

The springtime sublimation process of Mars’ southern seasonal polar CO2 ice cap features dark fan-shaped de- posits appearing on the top of the thawing ice sheet. The fan material likely originates from the surface below the ice sheet, brought up via CO2 jets breaking through the seasonal ice cap. Once the dust and dirt is released into the atmosphere, the material may be blown by the surface winds into the dark streaks visible from orbit. The location, size and direction of these fans record a number of parameters important to quantifying seasonal winds and sublimation activity, the most important agent of geological change extant on Mars. We present results of a systematic mapping of these south polar seasonal fans with the Planet Four online citizen science project. Planet Four enlists the general public to map the shapes, directions, and sizes of the seasonal fans visible in orbital images. Over 80,000 volunteers have contributed to the Planet Four project, reviewing 221 images, from Mars Reconnaissance Orbiter’s HiRISE (High Resolution Imaging Science Experiment) camera, taken in southern spring during Mars Years 29 and 30. We provide an overview of Planet Four and detail the processes of combining multiple volunteer assessments together to generate a high delity catalog of ∼ 400000 south polar seasonal fans. We present the results from analyzing the wind directions at several locations monitored by HiRISE over two Mars years, providing new insights into polar surface winds

Formation of a copper(II)-tyrosyl complex at the active site of lytic polysaccharide monooxygenases following oxidation by H2O2

Hydrogen peroxide is a cosubstrate for the oxidative cleavage of saccharidic substrates by copper-containing lytic polysaccharide monooxygenases (LPMOs). The rate of reaction of LPMOs with hydrogen peroxide is high, but it is accompanied by rapid inactivation of the enzymes, presumably through protein oxidation. Herein, we use UV− vis, CD, XAS, EPR, VT/VH-MCD, and resonance Raman spectroscopies, augmented with mass spectrometry and DFT calculations, to show that the product of reaction of an AA9 LPMO with H2O2 at higher pHs is a singlet Cu(II)−tyrosyl radical species, which is inactive for the oxidation of saccharidic substrates. The Cu(II)−tyrosyl radical center entails the formation of significant Cu(II)−(●OTyr) overlap, which in turn requires that the plane of the d(x2−y2) SOMO of the Cu(II) is orientated toward the tyrosyl radical. We propose from the Marcus cross-relation that the active site tyrosine is part of a “hole-hopping” charge-transfer mechanism formed of a pathway of conserved tyrosine and tryptophan residues, which can protect the protein active site from inactivation during uncoupled turnover

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum